Jonathan Rameseder, PhD

Austria | Fulbright S&T Alumnus 2008 | Massachusetts Institute of Technology | Computational Biology

profilepicramesederjonathanJonathan Rameseder is a Ph.D. candidate in Computational Systems Biology at the Massachusetts Institute of Technology (MIT) where he develops novel computational methods to investigate how cells respond to DNA damage. Since damage of cellular DNA contributes both to cancer development, and to cancer treatment by radiotherapy and chemotherapy, a detailed understanding of the DNA damage response could lead to the discovery of new molecular components that may be targets for therapeutic intervention in cancer.

However, signal transduction networks like the DNA damage response are of enormous complexity. A promising approach to understand how biological information is transmitted through such networks are microscopy-based high-throughput RNA interference screens, in which collections of genes are inactivated to explore what roles they play in the pathways of interest. Jonathan develops advanced computational and statistical methods to analyze the wealth of data acquired through such screens.

Jonathan received his undergraduate degree from the Upper Austria University of Applied Sciences and conducted research at Singapore’s Agency for Science, Technology and Research, the Swiss Federal Institute of Technology, the Friedrich Miescher Institute, the European Bioinformatics Institute, and the Whitehead Institute.

In his free time, Jonathan enjoys hiking, fitness training and traveling.

2008 Fulbright S&T Fellow Jonathan Rameseder received the Howard Hughes Medical Institute’s HHMI International Student Research Fellowship.